[Anti-amnestic activities of 3-hydroxy-3-pyrroline-2-one derivatives].

Autor: Shuklina NS; Pharmacology Department, Perm State Pharmaceutical Academy, ul. Lenina 48, Perm, 614000 Russia., Kolla VE
Jazyk: ruština
Zdroj: Eksperimental'naia i klinicheskaia farmakologiia [Eksp Klin Farmakol] 2003 Nov-Dec; Vol. 66 (6), pp. 12-5.
Abstrakt: The antiamnesic properties of a series of new 3-hydroxy-3-pyrrolin-2-on derivatives structurally analogous to pyrrolidinone nootropes and GABA were studied on a model of amnesia of the passive avoidance conditioned reflex. The screening revealed compounds whose antiamnesic action is comparable with that of piracetam.
Databáze: MEDLINE