| Autor: |
de Silva DG; Department of Child Health, King's College School of Medicine and Dentistry, London, U.K., Candy DC, Mendis LN, Chart H, Rowe B |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of infection [J Infect] 1992 Nov; Vol. 25 (3), pp. 273-8. |
| DOI: |
10.1016/0163-4453(92)91539-n |
| Abstrakt: |
A total of 192 samples of serum from 113 Sri Lankan patients with clinical dysentery was examined for antibodies of the IgM class to the lipopolysaccharides (LPSs) of Shigella dysenteriae-1 and Escherichia coli O157:H7. By means of ELISA and immunoblotting, 59 patients were found to have serum antibodies to the LPS of S. dysenteriae-1 only. Four samples from one patient were found to contain serum antibodies to the LPSs of both S. dysenteriae-1 and E. coli O157:H7. Antibodies to the LPS of S. dysenteriae-1 were also detected in 16 samples from 25 children, from Sri Lanka, with no previous history of dysentery; one of these children also had antibodies to the LPS of E. coli O157:H7. Analysis of 16 samples from apparently healthy children in the U.K. showed that only one serum contained antibodies to the LPS of S. dysenteriae-1. This patient had a history of recent travel to Pakistan. The isolation of S. dysenteriae-1 remains the preferred test for the diagnosis of bacillary dysentery. The use of serology as a means of providing evidence of infection with S. dysenteriae-1, however may prove to be a useful adjunct to cultural techniques but needs to be validated in an area where this organism is endemic. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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