Visual object agnosia and pure word alexia: correlation of functional magnetic resonance imaging and lesion localization.

Autor: Salvan CV; Department of Radiology, Division of Neuroradiology, Medical College of Wisconsin, 9200 W. Wisconsin Avenue, Milwaukee, WI 53226, USA., Ulmer JL, DeYoe EA, Wascher T, Mathews VP, Lewis JW, Prost RW
Jazyk: angličtina
Zdroj: Journal of computer assisted tomography [J Comput Assist Tomogr] 2004 Jan-Feb; Vol. 28 (1), pp. 63-7.
DOI: 10.1097/00004728-200401000-00010
Abstrakt: We present a case of a 64-year-old, right-handed female with a metastatic breast cancer lesion involving the left posterior inferior temporal lobe causing complete loss of the ability to recognize visually common objects and words. After her symptoms resolved on corticosteroid therapy, functional magnetic resonance imaging (fMRI) mapping demonstrated strong left-hemispheric dominance for word recognition and right-hemispheric dominance for object recognition. The case illustrates the relationships among ventral occipito-temporal cortical activation, lesion localization, and lesion-induced deficits of higher visual function. The relationship between hemispheric dominance determined by fMRI and risk of postoperative deficit depends on the specific visual function of interest.
Databáze: MEDLINE