Mesial temporal lobe epilepsy and hippocampal sclerosis: cognitive function assessment in Hispanic patients.

Autor: Oddo S; Epilepsy Center, Neurology Division, Ramos Mejia Hospital, Av. Scalabrini Ortiz 2330 1 degrees E, Capital Federal, CP: 1425, Buenos Aires, Argentina. silviaoddo@hotmail.com, Solís P, Consalvo D, Giagante B, Silva W, D'Alessio L, Centurión E, Saidón P, Kochen S
Jazyk: angličtina
Zdroj: Epilepsy & behavior : E&B [Epilepsy Behav] 2003 Dec; Vol. 4 (6), pp. 717-22.
DOI: 10.1016/j.yebeh.2003.09.008
Abstrakt: Purpose: The goal of this study was to assess the cognitive function status in patients with mesial temporal lobe epilepsy and hippocampal sclerosis (TLE+HS) to determine their cognitive function profile and to correlate material-specific memory deficits with HS laterality diagnosed by MRI.
Methods: Seventy-one patients were assessed with a neuropsychological protocol that includes IQ, attention, handedness, verbal memory, visual memory, language, and the executive function. chi(2) and correlation tests were used.
Results: Memory impairment was found in 46 patients (66%): patients without any memory deficit (n=25), patients with verbal memory deficit (n=21), patients with visual memory deficit (n=17), patients with deficit for both types of memory (n=8). Correlation between MRI lesion and memory was 66%. Language was impaired in 33 patients (46%). Eighteen patients (25%) had a deficit of the executive function.
Conclusions: Patients with TLE+HS presented with a deficit in material-specific episodic memory correlating in large proportion with HS lateralization. We also found language and executive function impairments.
Databáze: MEDLINE
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