| Autor: |
Griadunov DA, Mikhaĭlovich VM, Lapa SA, Rudinskiĭ NI, Barskiĭ VE, Chudinov AV, Zasedatelev AS, Mirzabekov AD |
| Jazyk: |
ruština |
| Zdroj: |
Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 2003 (4), pp. 24-7. |
| Abstrakt: |
A method of multiplex polymerase chain reaction (PCR) with subsequent hyoridization on oligonucleotide microchips was worked out to identify the Mycobacterium tuberculosis complex and to determine simultaneously the bacterial sensitivity to 2 first-line drugs, i.e. rifampin and isoniazid. The method provides for detecting above 95% of rifampin-resistant and around 80% of isoniazid-resistant strains within 1 day. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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