| Autor: |
Cotham WE; Department of Chemistry and Biochemistry, Graduate Science Research Center, University of South Carolina, 631 Sumter Street, Columbia, SC 29208, U.S.A., Hinton DJ, Metz TO, Brock JW, Thorpe SR, Baynes JW, Ames JM |
| Jazyk: |
angličtina |
| Zdroj: |
Biochemical Society transactions [Biochem Soc Trans] 2003 Dec; Vol. 31 (Pt 6), pp. 1426-7. |
| DOI: |
10.1042/bst0311426 |
| Abstrakt: |
RNase A (1 mM) was incubated with glucose (0.4 M) at 37 degrees C for up to 14 days in phosphate buffer (0.2 M, pH 7.4), digested with trypsin and analysed by LC-MS. The major sites of fructoselysine formation were Lys(1), Lys(7), Lys(37) and Lys(41). Three of these sites (Lys(7), Lys(37) and Lys(41)) were also the major sites of N epsilon-(carboxymethyl)lysine formation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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