Expression of c-fos protein in lumbosacral spinal cord in response to vaginocervical stimulation in rats.

Autor: Chinapen S; Institute of Animal Behavior, Rutgers University, Newark, NJ 07102., Swann JM, Steinman JL, Komisaruk BR
Jazyk: angličtina
Zdroj: Neuroscience letters [Neurosci Lett] 1992 Sep 28; Vol. 145 (1), pp. 93-6.
DOI: 10.1016/0304-3940(92)90211-o
Abstrakt: The pattern of vaginocervical stimulation-evoked expression of the proto-oncogene c-fos in lumbar 5-sacral 1 segments of the spinal cord of ovariectomized adult rats was mapped using immunocytochemistry. A calibrated force of mechanostimulation was applied to the vaginal cervix of experimental animals and to the perineum of control animals while they were gently restrained. The number of cells expressing c-fos was significantly greater in the experimental than the control animals in laminae I, IV, V-VI and X. The implications of the present findings for elucidating the spinal pathways mediating the various behavioral, neuroendocrine and autonomic effects of vaginocervical stimulation (VS) are discussed.
Databáze: MEDLINE