[Molecular mechanisms of stabilizing proteolytic enzymes. Model of a thermolysin-like microbial metalloproteinase].

Autor: Demidiuk IV; Institute of Molecular Genetics, Russian Academy of Sciences, pl. Kurchatova 2, Moscow, 123182 Russia., Zabolotskaia MV, Safrina DR, Kostrov SV
Jazyk: ruština
Zdroj: Bioorganicheskaia khimiia [Bioorg Khim] 2003 Sep-Oct; Vol. 29 (5), pp. 461-9.
Abstrakt: The molecular mechanisms that ensure the stability of proteolytic proteins are discussed. The autolytic pathway of protease degradation is emphasized. Experiments aimed at increasing the thermal stability of thermolysin-like metalloproteases are comprehensively described.
Databáze: MEDLINE