| Autor: |
Hochstenbag MM; Department of Respiratory Medicine, University Hospital Maastricht, P.O. Box 5800, 6202 AZ Maastricht, The Netherlands., Twijnstra A, Hofman P, Wouters EF, ten Velde GP |
| Jazyk: |
angličtina |
| Zdroj: |
Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2003 Nov; Vol. 42 (2), pp. 189-93. |
| DOI: |
10.1016/s0169-5002(03)00291-5 |
| Abstrakt: |
Magnetic resonance imaging (MRI) of the brain and extensive neurological examination by a neurologist was performed as part of initial staging evaluation of 91 neurologic asymptomatic patients with large cell carcinoma or adenocarcinoma of the lung. Patients were followed up for at least 6 months. Evidence of metastatic brain disease was documented in 13 (14%) patients. Two of these patients were found suspective of brain metastases (BM) by the neurologist. The detection of BM resulted in upstaging of 1 (3%) patient in stage I/II, 4 (21%) patients in stage IIIA and 2 (11%) patients in IIIB. Especially for patients in stage III this upstaging is of importance as aggressive locoregional treatment can be abandoned. Evaluation of the brain with MRI is a sensitive method of detecting BM in neurologic asymptomatic patients and is recommended as part of the initial staging of patients with large cell carcinoma or adenocarcinoma of the lung in stage III. Additional examination by the neurologist is of little value to provide information of the neurologic status. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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