[The new agent G-1724: synthesis and test on murine models of trichuriasis and trichinosis].

Autor: Dobrovinskaia NA, Trusov SN, Fedianina LV, Veretennikova NL, Sevbo DP, Mikhaĭlitsyn FS
Jazyk: ruština
Zdroj: Meditsinskaia parazitologiia i parazitarnye bolezni [Med Parazitol (Mosk)] 2003 Jul-Sep (3), pp. 40-1.
Abstrakt: To search for new antihelminthics, the new compound N-[3-chloro-4-[(1-ethyl-2-benzimidazolyl) thio]phenyl]-2-hydroxy-3,5-dibromobenzamide (the agent G-1724) was synthesized and tested by using the models of trichocephaliasis (Trichocephalus muris) and trichinosis (Trichinella spiralis). The tests demonstrated that this agent had an nematocidal effect (71-78%).
Databáze: MEDLINE