In vivo lipoprotein binding assay of the insect exchangeable apolipoprotein, apolipophorin-III.

Autor: Chetty PS; 147 Noble Research Center, Department of Biochemistry and Molecular Biology, Oklahoma State University, Stillwater, OK 74078, USA. jose@biochem.okstate.edu, Arrese EL, Soulages JL
Jazyk: angličtina
Zdroj: Protein and peptide letters [Protein Pept Lett] 2003 Oct; Vol. 10 (5), pp. 469-73.
DOI: 10.2174/0929866033478681
Abstrakt: An original method for the study of the lipid binding properties of exchangeable apolipoproteins is reported. Binding of Locusta migratoria apolipophorin-III to Manduca sexta low-density lipophorin (LDLp) and high-density lipophorin (HDLp) was studied in vivo. This assay could be used useful to investigate the effect of mutations in the lipid binding properties of exchangeable apolipoproteins under physiological conditions.
Databáze: MEDLINE