Seroprevalence and risk factors associated with Helicobacter pylori infection in blood donors in Salvador, Northeast-Brazil.

Autor: Lyra AC; Gastroenterology and Hepatology Service of Federal University of Bahia and Gastro-Hepatology Service of São Rafael Hospital, Salvador, BA, Brazil., Santana G, Santana N, Silvany-Neto A, Magalhães E, Pereira EM, Mascarenhas R, Lyra MC, Veiga A, Ferreira K, Zaterka S, Lyra LG
Jazyk: angličtina
Zdroj: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases [Braz J Infect Dis] 2003 Oct; Vol. 7 (5), pp. 339-45.
DOI: 10.1590/s1413-86702003000500009
Abstrakt: Helicobacter pylori plays an important role in the etiology of peptic ulcer disease. Its prevalence appears to be higher in developing countries. We evaluated the seroprevalence of H. pylori and risk factors associated with infection in voluntary blood donors who attended the main blood center of the city of Salvador, Brazil. The subjects responded to an epidemiological questionnaire, with information about sex, age, race, lifestyle, social-economic level indicators, and residence and hygiene conditions. Anti-H. pylori antibody was determined by ELISA (Cobas Core, Roche). Three hundred and seven subjects were included in the study. Anti-H. pylori antibody results were indeterminate in 33 individuals (10.8%), who were excluded from analysis. Among the remaining 274 subjects, 187 (68.2%) were anti-H. pylori positive. Based on multivariate logistic regression analysis three variables were found to be significantly associated with a higher prevalence of H. pylori infection: absence of plumbing in the residence during childhood, a history of rainwater invading the dwelling during childhood, and low ingestion of milk.
Databáze: MEDLINE