[Analysis of deletions in the dystrophin gene by the multiplex amplification method in patients suffering from Duchenne's muscular dystrophy].

Autor: Malysheva OV, Poliakov AV, Zaĭtseva SP, Malygina NA, Gorbunova VN, Evgrafov OV, Makarov VG, Krasil'nikov VV, Baranov VS, Vadalian LO
Jazyk: ruština
Zdroj: Molekuliarnaia genetika, mikrobiologiia i virusologiia [Mol Gen Mikrobiol Virusol] 1992 May-Jun (5-6), pp. 27-31.
Abstrakt: Multiplex polymerase chain reaction was carried out with the material from 68 patients suffering from Duchenne muscular dystrophy in Moscow and Leningrad clinics. Six pairs of oligoprimers were used. Deletions were detected in the material from 22 patients. A new type of deletion was found. Data on deletion frequencies and spectrum were compared with the results published by other authors.
Databáze: MEDLINE