| Autor: |
Il'chenko AP; Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, pr. Nauki 5, Pushchino, Moscow Oblast, 142290 Russia., Cherniavskaia OG, Shishkanova NV, Finogenova TV |
| Jazyk: |
ruština |
| Zdroj: |
Mikrobiologiia [Mikrobiologiia] 2003 Jul-Aug; Vol. 72 (4), pp. 470-5. |
| Abstrakt: |
A comparative assay of nitrogen metabolism enzymes in the Yarrowia lipolytica mutant N1 grown under conditions promoting the overproduction of either alpha-ketoglutaric acid (KGA) or citric acid showed that the overproduction of KGA correlates with an increase in the activities of the NAD- and NADP-linked glutamate dehydrogenase, glutamic-pyruvic transaminase, and glutamic-oxaloacetic transaminase reactions. These reactions are likely to be responsible for the overproduction of KGA by this mutant. In contrast, the overproduction of citric acid correlated with a decline in the activities of the NAD- and NADP-linked glutamate dehydrogenases and with an increase in the activities of glutamine synthetase and glutamate synthase. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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