| Autor: |
Greer JL; Department of Poultry Science, Texas Agricultural Experiment Station, Texas A&M University System, College Station 77843-2472., Hargis PS |
| Jazyk: |
angličtina |
| Zdroj: |
Comparative biochemistry and physiology. B, Comparative biochemistry [Comp Biochem Physiol B] 1992 Sep; Vol. 103 (1), pp. 9-13. |
| DOI: |
10.1016/0305-0491(92)90405-g |
| Abstrakt: |
1. An enzymatic assay for microsomal acyl-CoA: cholesterol acyltransferase (ACAT) activity in chicken hepatic tissues was developed using silicic acid chromatography. 2. ACAT activity was increased in response to liver cytosolic protein preparations suggesting the presence of cytosolic modulators of the enzyme. 3. Fractions containing low molecular weight proteins (12-15 kDa) prepared by molecular sieve chromatography also stimulated ACAT activity. 4. Liver-FABP was specifically implicated as a cytosolic modulator of ACAT activity in chicken liver tissue. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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