| Autor: |
Rao S; Orthopaedic Hospital Spine Center, Los Angeles, California., Badani K, Schildhauer T, Borges M |
| Jazyk: |
angličtina |
| Zdroj: |
Spine [Spine (Phila Pa 1976)] 1992 Oct; Vol. 17 (10 Suppl), pp. S407-12. |
| DOI: |
10.1097/00007632-199210001-00011 |
| Abstrakt: |
Of 48 patients with spinal metastases treated at the Kenneth J. Norris Cancer Center at The University of Southern California Medical Center in Los Angeles, California between 1984 and 1987, 19 consecutive patients with cervical metastatic disease were identified and followed until death or remission. Prostate, breast, and lung neoplasms accounted for 57% of the cervical metastases. Associated nonspinal skeletal, extraskeletal, or multiple-level spinal metastases were seen in 95% of patients. Mean time from diagnosis of primary tumor to cervical metastasis was 29 months and mean survival after that was 14.7 months. Pain was the initial symptom in 89% of cases. No patient had neurologic deficit and three (16%) had slight radiographic collapse and deformity. Only one (5%) patient had documented instability. All patients had nonoperative treatment with radiotherapy, chemotherapy, or a combination. Irrespective, the pain recurred in all patients by 6 months. Nonoperative treatment may be appropriate in the absence of significant neurologic deficit or instability. The return of symptoms by 6 months warrants alternative modes of therapy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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