Ocular manifestation of systemic histiocytosis in a dog.

Autor: Scherlie PH Jr; Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853., Smedes SL, Feltz T, Dougherty SA, Riis RC
Jazyk: angličtina
Zdroj: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 1992 Oct 15; Vol. 201 (8), pp. 1229-32.
Abstrakt: A 3-year-old sexually intact female Bernese Mountain Dog was referred for treatment of a descemetocele of the left eye. Physical examination revealed bilateral exophthalmos and scleral thickening, multiple cutaneous nodules, and mandibular paralysis in addition to ulcerative keratitis associated with a Pseudomonas infection. One year prior to examination, a biopsy specimen of the episcleral tissue from the right eye had been interpreted as nodular granulomatous episclerokeratitis (fibrous histiocytoma). Immunosuppressive treatment prior to referral had not resulted in remission of the ocular lesions. When we examined the biopsy specimen, we interpreted the lesions to represent episcleral involvement of systemic histiocytosis. Because of the poor prognosis, the dog was euthanatized.
Databáze: MEDLINE