[Effect of various metabolic poisons on the nature of contraction of the straight muscle of the abdomen of frog].

Autor: Esyrev OV, Murzakhmetova MK, Omarova RD
Jazyk: ruština
Zdroj: Tsitologiia [Tsitologiia] 1976 Nov; Vol. 18 (11), pp. 1378-82.
Abstrakt: A slow decline of responses was obtained after acetylcholine and KCl-stimulation of musculus rectus abdominis of the lake frog in the presence of antymicin A (0.27 mcg/ml). Dinitrophenol (up to 6.7.10(-4) M) as well as antymicin A inhibited the muscle contractility, with the effect being reversible. Muscle contraction ensued the application of dinitrophenol in concentration more than 6.7.10(-4)M. Decurarization ability of dinitrophenol was established. Mechanisms of disruption of the excitation--contraction coupling due to metabolic inhibitors are discussed.
Databáze: MEDLINE