HEMOGLOBIN SOLUBILITY AND ALPHA-CHAIN STRUCTURE IN CROSSES BETWEEN TWO INBREAD MOUSE STRAINS.

Autor: HUTTON JJ, SCHWEET RS, WOLFE HG, RUSSELL ES
Jazyk: angličtina
Zdroj: Science (New York, N.Y.) [Science] 1964 Jan 17; Vol. 143 (3603), pp. 252-3.
DOI: 10.1126/science.143.3603.252
Abstrakt: In genetic crosses between mouse strains with low and high solubilities of hemoglobin, solubility segregated as a Mendelian unit and appeared to be determined by the alleles controlling alpha-chain structure. New data eliminate close linkage between the alpha-chain locus and genetic markers in linkage groups Ill, IV, XI, XIII, and XVI. Simplified methods are presented for screening differences inalpha-chain peptides and solubility.
Databáze: MEDLINE