Dowling-Degos' disease mimicking chloracne.

Autor: Kershenovich J; Department of Dermatology, University of California, San Francisco 94143., Langenberg A, Odom RB, LeBoit PE
Jazyk: angličtina
Zdroj: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 1992 Aug; Vol. 27 (2 Pt 2), pp. 345-8.
DOI: 10.1016/0190-9622(92)70197-n
Abstrakt: We describe a patient with clinical features that resembled severe chloracne; however, histopathologic findings revealed a reticulated pigmented anomaly. Innumerable comedones, many cysts, acneiform scarring, and flexural and facial pigmentation were noted in this patient, who is a machinist. A serum test for polychlorinated biphenyl was negative, which eliminated a diagnosis of chloracne. The spectrum of clinical features of the histologically well-defined Dowling-Degos' disease is discussed; in this disease lesions can be flexural or acral and can appear as macules, comedones, or cysts.
Databáze: MEDLINE