| Autor: |
Greenberg F; Institute for Molecular Genetics, Houston, TX 77030., Faucett A, Rose E, Bancalari L, Kardon NB, Mizejewski G, Haddow JE, Alpert E |
| Jazyk: |
angličtina |
| Zdroj: |
American journal of obstetrics and gynecology [Am J Obstet Gynecol] 1992 Aug; Vol. 167 (2), pp. 509-11. |
| DOI: |
10.1016/s0002-9378(11)91441-0 |
| Abstrakt: |
Although alpha-fetoprotein may play a role in fetal immune function or in maintenance of osmotic pressure, its exact function is unknown. We report two infants documented to have congenital deficiency of alpha-fetoprotein. One infant had cord blood levels less than 0.5 ng/ml. The second infant had a neonatal level of 120 ng/ml, which is about 2% of the usual concentration for a term newborn. These infants document the existence of congenital deficiency of serum alpha-fetoprotein. Because it is homologous to albumin, congenital deficiency of alpha-fetoprotein may be analogous to analbuminemia, a benign genetic trait. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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