| Autor: |
NISONOFF A, WISSLER FC, LIPMAN LN |
| Jazyk: |
angličtina |
| Zdroj: |
Science (New York, N.Y.) [Science] 1960 Dec 09; Vol. 132 (3441), pp. 1770-1. |
| DOI: |
10.1126/science.132.3441.1770 |
| Abstrakt: |
The molecular weight of the active, major component isolated from a peptic digest of rabbit antibody was found to be 106,000. After treatment with a disulfide-splitting reagent, the molecular weight was 56,000, and the products migrated as a single peak in the ultracentrifuge. he univalent fragments thus formed can be partially recombined by passage through IR-120 cation-exchange resin at room temperature or by treatment with a difunctional organic mercurial. Some splitting of the pepsin-treated antibody molecule occurs on carboxymethylcellulose at pH 5.4. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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