| Autor: |
Morra L; Istituto Scientifico di Medicina Interna (ISMI), University of Genoa, Italy., Ponassi GA, Gurreri G, Moccia F, Mela GS, Bessone G |
| Jazyk: |
angličtina |
| Zdroj: |
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 1990; Vol. 44 (1), pp. 53-6. |
| DOI: |
10.1016/0753-3322(90)90070-p |
| Abstrakt: |
Blood T lymphocyte subsets have been studied using monoclonal antibodies in 10 chronic uremic patients treated with maintenance hemodialysis. Both total T lymphocytes identified by the antibody OKT3, and the helper-inducer T lymphocyte subset identified by the antibody OKT4 were found to be significantly lower than normal. The cytotoxic-suppressor T cell subset was only moderately, even if significantly reduced, so that the T4/T8 ratio in uremic patients was significantly lower than normal. These data provide an additional contribution to the interpretation of immunological and hematological deficiencies observed in chronic uremia. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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