Outcome of cryosurgery for cervical intraepithelial neoplasia in a developing country.

Autor: Olatunbosun OA; Department of Obstetrics and Gynaecology, Faculty of Health Sciences, Obafemi Awolowo University, Ile-Ife, Nigeria., Okonofua FE, Ayangade SO
Jazyk: angličtina
Zdroj: International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics [Int J Gynaecol Obstet] 1992 Aug; Vol. 38 (4), pp. 305-10.
DOI: 10.1016/0020-7292(92)91023-h
Abstrakt: Over a 2-year period cryosurgery was used to treat 73 women who were diagnosed by colposcopy and histologic studies to have cervical intraepithelial neoplasia (CIN). Follow-up was achieved for 70% at 5 years, a significant attendance rate in a developing country. The primary cure rate was 88.5% at 1 year and 90% at 5 years (excluding those lost to follow-up) in all patients with different grades of CIN. The therapy was free of major complications and we found no adverse effect of cryosurgery on subsequent reproductive function in those desiring pregnancy. We conclude that cryosurgery has gained wide acceptance in our geographic area particularly because of its low cost, efficacy and preservation of fertility. For these reasons we would strongly recommend its use provided adequate attention is paid to meticulous pretreatment evaluation and long-term follow-up after therapy.
Databáze: MEDLINE