The use of feline herpesvirus and baculovirus as vaccine vectors for the gag and env genes of feline leukaemia virus.

Autor: Wardley RC; Animal Health Therapeutics Research, Upjohn Company, Kalamazoo, Michigan 49001-0199., Berlinski PJ, Thomsen DR, Meyer AL, Post LE
Jazyk: angličtina
Zdroj: The Journal of general virology [J Gen Virol] 1992 Jul; Vol. 73 ( Pt 7), pp. 1811-8.
DOI: 10.1099/0022-1317-73-7-1811
Abstrakt: The env and gag genes from feline leukaemia virus were expressed in a thymidine kinase-negative feline herpes-virus and a baculovirus. Cats were vaccinated with various combinations of these recombinant viruses and 100% protection against feline leukaemia virus challenge was achieved using an immunization schedule which utilized both env and gag products delivered at both a mucosal and systemic site.
Databáze: MEDLINE