Immunotherapy in two foals with combined immunodeficiency, resulting in graft versus host reaction.

Autor: Ardans AA, Trommershausen-Smith A, Osburn BI, Mayhew IG, Trees C, Park MI, Sawyer M, Stabenfeldt GH
Jazyk: angličtina
Zdroj: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 1977 Jan 15; Vol. 170 (2), pp. 167-75.
Abstrakt: Immunotherapy was attempted in 2 Arabian foals with combined immunodeficiency. One foal was given a transplant of bone marrow from a selected full sibling, and 1 foal was given a fetal thymus transplant. Both foals died. Genetic evidence was obtained for survival of the transplanted tissues in both cases; however, a graft versus host reaction developed in the foal given the fetal thymus transplant.
Databáze: MEDLINE