| Autor: |
Dedov II, Gorel'sheva VA, Romanovskaia GA, Smirnova OM, Filippov IK, Sanfirova VM |
| Jazyk: |
ruština |
| Zdroj: |
Problemy endokrinologii [Probl Endokrinol (Mosk)] 1992 Nov-Dec; Vol. 38 (6), pp. 32-3. |
| Abstrakt: |
Studies of lipid peroxidation and antioxidant enzymic defense in red cell membranes in 23 patients with newly detected insulin-dependent diabetes mellitus have revealed a statistically significant (2-fold) elevation of malonic dialdehyde lipid peroxidation products and a trend to a rise in the levels of lipid peroxides. This is parallelled by a certain overstrain of the cellular antioxidant defense system. The authors discuss the usefulness of administering antioxidant therapy at the onset of the disease in order to prevent the toxic injury of beta-cells and vascular endothelium cells by lipid peroxidation products. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
