[Clinico-morphologic evaluation of susceptibility of glioblastoma to antiblastic therapy].

Autor: Semenova VM, Glavatskiĭ AIa
Jazyk: ruština
Zdroj: Klinicheskaia khirurgiia [Klin Khir (1962)] 1992 (12), pp. 31-4.
Abstrakt: Pathomorphology of a cerebral glioblastoma in 82 patients was studied. The most pronounced regressive changes in the glioblastoma occurred under the influence of a complex of antiblastic treatment, including polychemo- and immunotherapy, radiation therapy. A high degree of damaging effect on a glioblastoma tissue correlated with the longest lifetime of the patients--(22.8 +/- 2.6) mos. Of these patients, 26% survived more than 24 mos, 17%--more than 36 mos. In patients with chemo-resistant glioblastoma which retains morphologically a stability of its histologic structure, the mean survival almost didn't differ from that in the control group. Only few patients survived more than 1 year.
Databáze: MEDLINE