| Autor: |
Momynaliev KT; Institute of Physico-Chemical Medicine, Ministry of Health of the Russian Federation, Moscow, 119992 Russia. dhoroshun@nm.ru, Smirnova OV, Kudriavtseva LV, Govorun VM |
| Jazyk: |
ruština |
| Zdroj: |
Molekuliarnaia biologiia [Mol Biol (Mosk)] 2003 Jul-Aug; Vol. 37 (4), pp. 625-33. |
| Abstrakt: |
DNA macroarrays were used to characterize 17 Helicobacter pylori strains isolated in four geographic regions of Russia (Moscow, St. Petersburg, Kazan, and Novosibirsk). Of all genes, 1272 (81%) proved to occur in all strains and to constitute a functional core of the genome, and 293 (18.7%) were strain-specific and greatly varied among the H. pylori strains. Most (71%) of the latter had unknown functions; the remainder included restriction-modification genes (3-9%), transposition genes (2-4%), and genes coding for outer membrane proteins (2-4%). The Russian H. pylori strains did not differ in genome organization or in the number and distribution of strain-specific genes from strains isolated in other countries. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
