| Autor: |
Dudko ET, Tishchenko LM, Krivozubov VB |
| Jazyk: |
ruština |
| Zdroj: |
Likars'ka sprava [Lik Sprava] 1992 Nov-Dec (11-12), pp. 44-7. |
| Abstrakt: |
Results are described of a study of the population and subpopulation composition of lymphocytes in the course of use monochemotherapy (MTS) and polychemotherapy (PCT) in 60 patients with the tumorous form of B-cell chronic lympholeucosis using flow cytometric analysis. It was shown that cytostatic treatment in this form of hemoblastosis results in a reduction of the absolute number of B-lymphocytes due to reduction of general hemocytosis while the relative content of B-cells remained unchanged in MCT and is increased in PCT. A prolonged scheme of PCT is recommended for clinical use that possesses a distinct antitumour effect as compared with MCT and producing a significantly smaller immunosuppressive effect on the T-cell immune system that other schemes of cytostatic therapy. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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