Tweaking copper hydride (CuH) for synthetic gain. A practical, one-pot conversion of dialkyl ketones to reduced trialkylsilyl ether derivatives.

Autor: Lipshutz BH; Department of Chemistry and Biochemistry, University of California, Santa Barbara, California 93106, USA. lipschutz@chem.ucsb.edu, Caires CC, Kuipers P, Chrisman W
Jazyk: angličtina
Zdroj: Organic letters [Org Lett] 2003 Aug 21; Vol. 5 (17), pp. 3085-8.
DOI: 10.1021/ol035164+
Abstrakt: [reaction: see text] Variations in the reagents and stoichiometries used to generate CuH in situ, as well as the nature of the ligands present, have led to a very efficient and inexpensive method for effecting hydrosilylations of dialkyl ketones.
Databáze: MEDLINE