| Autor: |
Ramos AC; Department of Pediatrics, UFRJ, Rio de Janeiro, Brasil., Barrucand L, Elias PR, Pimentel AM, Pires VR |
| Jazyk: |
angličtina |
| Zdroj: |
Indian pediatrics [Indian Pediatr] 1992 Dec; Vol. 29 (12), pp. 1501-5. |
| Abstrakt: |
We studied the effect of carnitine supplementation in patients with diphtheria. Six hundred and twenty five children of diphtheria received either DL-carnitine (100 mg/kg/day in two divided doses orally for four days), or no carnitine, in addition to the routine treatment for diphtheria. The patients receiving carnitine (n = 327) and controls (n = 298) were matched for age, sex, duration of symptoms, grade of toxemia and immunization status. Patients receiving carnitine showed a significant reduction in incidence of myocarditis as compared to controls (p = 0.001). Cases with myocarditis receiving carnitine therapy showed a significant reduction in mortality as compared to controls (p < 0.001). In view of a significant decline in incidence and mortality of myocarditis in cases of diphtheria, we recommended that all cases with diphtheria should receive carnitine supplementation. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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