| Autor: |
Glenn GM; IOMAI Corporation, Gaithersburg, MD 20878, USA. gglenn@iomai.com, Kenney RT, Ellingsworth LR, Frech SA, Hammond SA, Zoeteweij JP |
| Jazyk: |
angličtina |
| Zdroj: |
Expert review of vaccines [Expert Rev Vaccines] 2003 Apr; Vol. 2 (2), pp. 253-67. |
| DOI: |
10.1586/14760584.2.2.253 |
| Abstrakt: |
The skin is an attractive target for vaccine delivery. Topical application of adjuvants results in potent immune responses and good safety profiles. Adjuvants can be coadministered in a patch with vaccine antigens (transcutaneous immunization) or similar delivery format, or administered separately with an injection or IS patch (Iomai), leading to enhanced immune responses. These observations have moved into the clinic, highlighting the likelihood that skin delivery of vaccines will play an important future role in vaccine applications. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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