| Autor: |
Rawal N; Department of Obstetrics and Gynaecology, Harold Wood Hospital, Romford, UK. nikitarawal@hotmail.com, Saridogan E, Weekes AW, Haq Khan N |
| Jazyk: |
angličtina |
| Zdroj: |
Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology [J Obstet Gynaecol] 2003 Jul; Vol. 23 (4), pp. 419-21. |
| DOI: |
10.1080/0144361031000120950 |
| Abstrakt: |
A prospective cytological and histological study was conducted in 627 women with borderline nuclear abnormality to assess its clinical significance in an attempt to reach a sound policy of management. The incidence of dyskaryosis was 10.9% at a 6-month repeat smear after the first borderline smear. The detection of cervical intraepithelial neoplasia (CIN) after two borderline smears increased to 21.15% on cytology and 40.75% on histology. Additionally, there were two cases of glandular intraepithelial neoplasia and one case of adenocarcinoma detected on histology after having borderline nuclear changes reported on cytology; 39.7% of these women with initial borderline cervical smear were under the age of 30 years. The high prevalence of borderline nuclear abnormality in younger women and a poor correlation between these abnormalities and severity of CIN suggest that repeat cytology is a less than optimal management for these women. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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