Developing human erythroid cells grown in transferrin-free medium utilize iron originating from extracellular ferritin.
| Autor: | Leimberg JM; Department of Human Nutrition and Metabolism, Faculty of Medicine, The Hebrew University, Jerusalem, Israel., Konijn AM, Fibach E |
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| Jazyk: | angličtina |
| Zdroj: | American journal of hematology [Am J Hematol] 2003 Jul; Vol. 73 (3), pp. 211-2. |
| DOI: | 10.1002/ajh.10355 |
| Abstrakt: | In addition to transferrin, ferritin can also function as a source of iron for heme synthesis (Gelvin D, et al. Blood 1996;88:3200-3207; Meyron-Holtz EG, et al. Blood 1999;94:3205-3211). In the present study we investigate the effect of external ferritin on the proliferation and hemoglobinization of human erythroid precursors grown in transferrin-free cultures. (Copyright 2003 Wiley-Liss, Inc.) |
| Databáze: | MEDLINE |
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