The HELLP-syndrome; maternal-fetal outcome and follow up of infants.
| Autor: | Roelofsen AC; Department of Obstetrics and Gynecology, Division of Obstetrics and Perinatal Medicine, University Hospital Groningen, Groningen, The Netherlands., van Pampus MG, Aarnoudse JG |
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| Jazyk: | angličtina |
| Zdroj: | Journal of perinatal medicine [J Perinat Med] 2003; Vol. 31 (3), pp. 201-8. |
| DOI: | 10.1515/JPM.2003.027 |
| Abstrakt: | Objective: To investigate maternal-fetal outcome of infants born after pregnancies complicated by (H)ELLP syndrome. Study Design: A retrospective cohort study was performed on patients with the HELLP or ELLP syndrome. Maternal and perinatal complications were recorded. The follow-up period of the infants was at least 18 months. A multivariate regression analysis was done to define the variables mostly contributing to adverse outcome. Results: No maternal deaths occurred. Eighteen infants of the HELLP group and six infants of the ELLP group died; total perinatal mortality was 17.6%. After 18 months four infants had major handicaps, making a total adverse outcome of 22.8%. Statistical analysis shows early gestational age, prolongation of pregnancy and administration of antihypertensive medication as the factors influencing outcome of the infants most. Conclusions: Prolongation of pregnancy contributed to better perinatal outcome, while administration of antihypertensive medication and early gestational age were related to a more unfavorable outcome. |
| Databáze: | MEDLINE |
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