| Autor: |
Magnus P; Department of Chemistry and Biochemistry, University of Texas at Austin, Austin, Texas 78712, USA. p.magnus@mail.utexas.edu, Matthews KS, Lynch V |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2003 Jun 12; Vol. 5 (12), pp. 2181-4. |
| DOI: |
10.1021/ol034683+ |
| Abstrakt: |
[reaction: see text] A general strategy for the formation of 1,3-cis-substituted tetrahydroisoquinolines is described from ortho-iodo imines involving Larock isoquinoline synthesis, addition of organolithium compounds to unactivated isoquinolines, and ionic hydrogenation. In addition, a new synthesis of lactams via an unprecedented azide cyclization in the presence of a sulfonium ion is described. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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