Autor: |
Sokolov IK, Belen'kiĭ EE, Tunitskaia TA, Kalugina GE, Briskin AI |
Jazyk: |
ruština |
Zdroj: |
Farmakologiia i toksikologiia [Farmakol Toksikol] 1976 Mar-Apr; Vol. 39 (2), pp. 167-73. |
Abstrakt: |
Administration of thyrocalcitonine (TCT) in doses of 0.1 and 1 Un/kg for 14 days prevented the development of myocarditis in rats receiving epinephrine (3 mg/kg) for 4 days reduced the death rate among the animals, increased their body weight and normalized the electrolytes composition in the heart. Given in a dose of 10 Un/kg the drug produced a less pronounced positive effect on the study values in the animals with experimentally-produced epinephrine lesion of the heart. According to the authors this may be occasioned by an intensified secretion of the parathyroid hormone in response to a multiple introduction of large TCT doses to the animals. |
Databáze: |
MEDLINE |
Externí odkaz: |
|