| Autor: |
Bondarenko LA; Chronoendocrinology Laboratory, V. Ya. Danilevskii Institute of Problems of Endocrine Pathology, Ukrainian Academy of Medical Sciences, 10 Artem Street, 61002 Khar'kov-2, Ukraine., Gubina-Vakulik GI |
| Jazyk: |
angličtina |
| Zdroj: |
Neuroscience and behavioral physiology [Neurosci Behav Physiol] 2003 May; Vol. 33 (4), pp. 405-9. |
| DOI: |
10.1023/a:1022859910477 |
| Abstrakt: |
The effects of stress induced by hypothermia (+4 degrees C for 3 h) on the pathways of serotonin metabolism in the pineal gland and on its structure were studied in adult male Wistar rats. These experiments showed that the melatonin-forming function of the epiphysis undergoes phasic changes during adaptation: there was a significant increase during the first 15 min, which was followed by gradual inhibition (to initial by 30 min) and then sharp suppression (at 3 h). Suppression of the functional activity of the pineal gland occurred because of exclusion of a proportion of pinealocytes from the process of active functioning. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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