[Prediction of the effectiveness of preoperative preparation of patients with fibro-cavernous pulmonary tuberculosis].

Autor: Titarenko OT, Esmedliaeva DS, D'iakova ME, Avetisian AO, Riasnianskaia TB, Perova TL
Jazyk: ruština
Zdroj: Problemy tuberkuleza i boleznei legkikh [Probl Tuberk Bolezn Legk] 2003 (4), pp. 41-4.
Abstrakt: Sixty-three patients with fibrocavernous pulmonary tuberculosis were examined before and 1 month after preoperative therapy with antituberculosis agents. The time course of changes in the clinical and X-ray characteristics of the severity of the disease were compared with the alterations of different biochemical indices, including acute-phase proteins, proteolysis inhibitors, intoxication severity. It was demonstrated that improvement of clinical and X-ray characteristics of the severity of a process after preoperative preparation could be predicted with an accuracy of 83% from the baseline serum concentrations of albumin and ceruloplasmin. The accuracy of prediction does not increase when the levels of protease inhibitors, C-reactive protein, adenosine deaminase, medium-weight molecules are simultaneously studied. The likelihood of the clinical and X-ray characteristics becoming better is higher with enhanced ceruloplasmin activity and decreased albumin levels.
Databáze: MEDLINE