Stereoselective entry to beta-linked C-disaccharides using a carbon-Ferrier reaction.

Autor: Gemmell N; School of Chemistry, University of Reading, Whiteknights, Reading, RG6 6AD, UK., Meo P, Osborn HM
Jazyk: angličtina
Zdroj: Organic letters [Org Lett] 2003 May 15; Vol. 5 (10), pp. 1649-52.
DOI: 10.1021/ol030023t
Abstrakt: [structure: see text] The synthesis of unsaturated beta-linked C-disaccharides by the Lewis acid-mediated reaction of 3-O-acetylated glycals with monosaccharide-derived alkenes is described. Deprotection and selective hydrogenation of an exocyclic carbon-carbon double, in the presence of an endocyclic double bond, for representative targets is also illustrated.
Databáze: MEDLINE