Synthesis and cytotoxic activity of 1,3-benzodioxole derivatives. Note II.

Autor: Micale N; Dipartimento Farmaco-Chimico, Università di Messina, Viale Annunziata, Messina 98168, Italy. nmicale@pharma.unime.it, Zappalà M, Grasso S
Jazyk: angličtina
Zdroj: Farmaco (Societa chimica italiana : 1989) [Farmaco] 2003 May; Vol. 58 (5), pp. 351-5.
DOI: 10.1016/S0014-827X(03)00053-3
Abstrakt: A series of 1,3-benzodioxoles (2-12) were synthesized and evaluated for their in vitro ability to inhibit the growth of three human tumor cell lines. No cytotoxic effects were noticed with any of the test compounds at a concentration of 10(-4) M.
Databáze: MEDLINE