[Evaluation of endothelial permeability in brain tumors by dynamic magnetic resonance tomography with magnevist contrast imaging on low-field MR-tomograph].

Autor: Usov VIu; Research Institute of Cardiology, Tomsk Research Center, Russian Academy of Medical Sciences, Tomsk Regional Clinical Hospital., Velichko OB, Borodin OIu, Garganeev AB, Shikunov AA, Boklag ON
Jazyk: ruština
Zdroj: Vestnik rentgenologii i radiologii [Vestn Rentgenol Radiol] 2001 May-Jun (3), pp. 22-9.
Abstrakt: In order to study the endothelial permeability to hydrophilic macromolecules in brain tumors we have developed a technique based on Gjedde-Rutland-Patlak approach to dynamic MRI study with Gd-DTPA injected intravenously, performed with low-field MRI tomograph Magnetom Open (Siemens medical). 27 patients with various brain tumors were referred for the study. The indices of Gd-DTPA transport to tumor tissue (KGd-DTPA) vary substantially, depending on the degree of malignancy and deliver essential information on microvascular permeability of tumor capillary bed.
Databáze: MEDLINE