| Autor: |
Kamzolova SV; Laboratory of Aerobic Metabolism of Microorganisms, G.K. Skryabin Institute of Biochemistry and Physiology of Microorganisms, Russian Academy of Sciences, p-t Nauki 5, Pushchino, Moscow region 142290, Russia. kamzolova@rambler.ru, Shishkanova NV, Morgunov IG, Finogenova TV |
| Jazyk: |
angličtina |
| Zdroj: |
FEMS yeast research [FEMS Yeast Res] 2003 Apr; Vol. 3 (2), pp. 217-22. |
| DOI: |
10.1016/S1567-1356(02)00188-5 |
| Abstrakt: |
During continuous cultivation of Yarrowia lipolytica N 1, oxygen requirements for growth and citric acid synthesis were found to depend on the iron concentration in the medium. A coupled effect of oxygen and iron concentrations on the functioning of the mitochondrial electron transport chain in Y. lipolytica N 1 was established. Based on the results obtained in continuous culture, conditions for citric acid production in a batch culture of Y. lipolytica N 1 were proposed. At relatively low pO(2) value and a high iron concentration, citric acid accumulation was as high as 120 g l(-1); the specific rate of citric acid synthesis reached 120 mg citric acid (g cells h)(-1). The mass yield coefficient was 0.87 and the energy yield coefficient was 0.31. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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