| Autor: |
Khan SA; Department of Psychology, The University of Western Ontario, Social Science Centre, London, Ontario, N6A 5C2, Canada., Ford K, Timney B, Everling S |
| Jazyk: |
angličtina |
| Zdroj: |
Experimental brain research [Exp Brain Res] 2003 May; Vol. 150 (1), pp. 68-74. Date of Electronic Publication: 2003 Mar 04. |
| DOI: |
10.1007/s00221-003-1400-1 |
| Abstrakt: |
It has been shown that saccade-related neurons in the superior colliculus (SC) display an increased level of prestimulus activity and a higher stimulus-related burst in action potentials preceding direction errors in the anti-saccade task compared with correct anti-saccades. From this, it has been hypothesized that errors occur when the incoming visual signal in the SC passes a threshold and triggers a reflexive saccade. This hypothesis predicts that an attenuated visual signal will reduce the number of direction errors. Since ethanol has been shown to have a suppressive effect on cortical visual event-related potentials (ERPs), the purpose of the present study was to investigate the effects of moderate ethanol consumption on anti-saccade performance. Under both placebo and ethanol conditions, we recorded ERPs and measured eye movements in male subjects during the performance of an anti-saccade task in which the fixation point disappeared 200 ms prior to stimulus presentation. Compared with the placebo condition, we found in the ethanol condition: (1). a decrease in ERP amplitudes during the gap period and after stimulus presentation, (2). an increase in the latencies of anti-saccades, and (3). a decrease in the percentage of direction errors. These data demonstrate the effects of ethanol on anti-saccade task performance and provide further support for the hypothesis that errors in the anti-saccade task are triggered by the incoming visual signal. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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