| Autor: |
Martirosov KS; State Research Center-Institute of Biophysics, Ministry of Health of Russia, Moscow, 123182 Russia., Grigor'ev IuG, Zorin VV, Borovkov MV |
| Jazyk: |
ruština |
| Zdroj: |
Radiatsionnaia biologiia, radioecologiia [Radiats Biol Radioecol] 2003 Jan-Feb; Vol. 43 (1), pp. 60-4. |
| Abstrakt: |
The experiments on dogs showed that Latranum, a selective blocker of serotonin 5-HT3-receptors, has a moderate capacity to modify emetic reaction caused by dophamin-stimulating action of Apomorphinum. These results, taking in account of our preliminary experimental data obtained by a model of early radiation-induced emetic reactions, show that the high antiemetic effect of Latranum may affect another mechanisms of the initiation of early radiation-inducing vomiting which do not connect immediately with the chemoreceptor trigger zone. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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