[Bioclinical correlations in bony metastases. Results of a prospective study. 60 cases].
| Autor: | Belhaj R; Institut Salah Azaiz Tunis., Boussen H, Ghanem A, Essafer S, Harzallah L, Ben Ayed F, Guemira F |
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| Jazyk: | francouzština |
| Zdroj: | La Tunisie medicale [Tunis Med] 2002 Nov; Vol. 80 (11), pp. 691-5. |
| Abstrakt: | Unlabelled: Our objective is to compare clinical and biological presentation of patients with bone metastatic disease. Patients and Methods: We collected prospectively 60 patients (adults and children) with proven bone metastasis. Tumors are mainly breast cancer (25/60) or nasopharyngeal carcinoma (8/60). All 8 children presented all with abdominal neuroblastoma. Bone lesions are lytic in 85% of cases. ALP and LDH seem to be sensitive markers for bone mestatasis with 75% and 80% pathologic rates. The highest rates have been observed in patients with multiple bones lesions (> 8) and painful metastases (more than 7 in the VAS). The median survival was 8 months (3 to 54). Conclusion: Even conventional, some biochemical markers as ALP and LDH remain useful in the diagnosis and prognosis in patients with proven bone metastasis. |
| Databáze: | MEDLINE |
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