[Prognostic value of pharmaco-EEG in depression treated with moclobemide].

Autor: Wiśniewski G; I Klinika Chorób Psychicznych AM w Gdańsku., Jakitowicz J, Nowicki Z, Pankiewicz P
Jazyk: polština
Zdroj: Psychiatria polska [Psychiatr Pol] 2002 Nov-Dec; Vol. 36 (6 Suppl), pp. 93-8.
Abstrakt: Ten women (age 41.90 +/- 5.67) with depressive episode (moderate, mild; ICD-10) were treated with moclobemide (450 mg). After 4 weeks two groups (each consists of 5 patients) with different response to the drug emerged (responders: improvement in Beck Inventory of Depression 13.6 +/- 2.9 and nonresponders: 2.0 +/- 2.4). FFT analysis of their EEG (taken before and after 4 weeks of treatment) showed some relative power differences in most bands of frequencies between groups, mostly marked for á (7-14 Hz), smaller for ä and â, but no differences for è were found. Alfa activity was relatively low after treatment in nonresponders and slightly higher in responders. However any of these results had statistical value.
Databáze: MEDLINE