Improvement in left ventricular dysfunction after surgical correction of mitral regurgitation.

Autor:	da Rocha AS; Division of Cardiac Surgery, National Institute of Cardiology Laranjeiras, Health Ministery, Rio de Janeiro, RJ, Brazil. ascrbr@centroin.com.br, da Rocha Nde N, Soares Rde C, Coimbra M, Ramos RG, Weksler C, Cruz Filho FE, da Silveira CG, da Silva PR
Jazyk:	English; Portuguese
Zdroj:	Arquivos brasileiros de cardiologia [Arq Bras Cardiol] 2003 Jan; Vol. 80 (1), pp. 13-8, 7-12. Date of Electronic Publication: 2003 Feb 19.
DOI:	10.1590/s0066-782x2003000100002
Abstrakt:	Objective: To evaluate whether left ventricular end-systolic (ESD) diameters < or = 51mm in patients (pt) with severe chronic mitral regurgitation (MR) are predictors of a poor prognosis after mitral valve surgery (MVS). Methods: Eleven pt (aged 36 +/- 13 years) were studied in the preoperative period (pre), median of 36 days; in the early postoperative period (post1), median of 9 days; and in the late postoperative period (post2), mean of 38.5 +/- 37.6 months. Clinical and echocardiographic data were gathered from each pt with MR and systolic diameter > or = 51 mm (mean = 57 +/- 4mm) to evaluate the result of MVS. Ten patients were in NYHA Class III/IV. Results: All but 2 pt improved in functional class. Two pt died from heart failure and infectious endocarditis 14 and 11 months, respectively, after valve replacement. According to ejection fraction (EF) in post2, we identified 2 groups: group 1 (n=6), whose EF decreased in post1, but increased in post2 (p=0.01) and group 2 (n=5), whose EF decreased progressively from post1 to post2 (p=0.10). All pt with symptoms lasting < or = 48 months had improvement in EF in post2 (p=0.01). Conclusion: ESD > or = 51 mm are not always associated with a poor prognosis after MVS in patients with MR. Symptoms lasting up to 48 months are associated with improvement in left ventricular function.
Databáze:	MEDLINE
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