| Autor: |
Burk KH, Drewinko B, Lichtiger B, Trujillo JM |
| Jazyk: |
angličtina |
| Zdroj: |
Cancer research [Cancer Res] 1976 Apr; Vol. 36 (4), pp. 1278-83. |
| Abstrakt: |
An analysis of cell cycle-dependent expression of tumor-associated antigen was performed on a human neurosarcoma cell line (T2 cells). The expression of sarcoma-associated tumor antigen on T2 cells was detected using test sera obtained from sarcoma patients; control sera were from patients with nonsarcoma neoplasias and from normal donors. Results indicate a progressive increase in the antigenic expression beginning in late mitosis and early G1 with maximum expression in mid-G1. Antigenic expression declines to minimum levels in S and G2-phase. Mechanisms responsible for this cycle-dependent fluctuation are presently unknown. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
